Find all hotels by Independent in San Mateo, CA

Compare rooms and suites by Independent in San Mateo with rates, reviews, and availability. Most hotels are fully refundable.

Independent San Mateo Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in San Mateo, San Francisco. Known for well-appointed rooms and friendly, personalized service, each of the top Independent San Mateo hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some San Mateo Independent locations may even offer extra little benefits and discounts for frequent travelers.

Recent reviews of San Mateo hotels
Expedia 亿客行 verified reviews

Hyatt Regency San Francisco

Hyatt Regency San Francisco

5/5 Excellent
Family Stay
"Family and I had a wonderful stay. Very clean and comfortable hotel. The staff were friendly and helpful. We had a few appetizers and drinks in the evening at the restaurant and it was all very well served and delicious. The breakfast was not worth the price, in my opinion, nonetheless it was appetizing. We will be back!"
A verified traveler stayed at Hyatt Regency San Francisco
Posted 17 hours ago
Hyatt Regency San Francisco