You can get a cheap car rental near Mayo Clinic, but a few factors will determine the cost of your ride. Among these are your travel dates, pick-up and drop-off points and any extras like a toddler seat. Finding a car that fits your needs and budget is easy with Expedia. Take a glimpse at our exclusive deals from a wide range of car rental companies, and then fasten your seat belt and explore Mayo Clinic and beyond from behind the wheel.